Cascadia Innovation Corridor 2025: Building a Bioregional Future Together

October 28–29, 2025 | Sheraton Grand, Seattle

The Cascadia Department of Bioregion is honored to participate in this year’s Cascadia Innovation Corridor Conference, a cross-border gathering that brings together business leaders, policymakers, and visionaries from across Oregon, Washington, and British Columbia. As we step into a future shaped by bold innovation, the Department is proud to advocate for a bioregional approach to regeneration, infrastructure, and identity within this growing megaregion.

What Is the Cascadia Innovation Corridor?

The Cascadia Innovation Corridor is the shared visionary framework uniting the Pacific Northwest as one of 16 mega-regions in North America. Spanning from Portland, Oregon to Vancouver, British Columbia, this cross-border initiative goes beyond economics—recognizing our shared ecologies, values, and cultures. Cascadia is a place where environmental stewardship meets cutting-edge technology, and where collaboration across cities, sectors, and sovereign borders is driving the vision for what could become the world’s first sustainable mega-region.

From clean energy to transportation, housing, and agriculture, the Innovation Corridor fosters bold, cross-sectoral partnerships to shape a resilient, prosperous, and just future for all who call Cascadia home.

Innovation with Roots

The theme of this year’s gathering—celebrating the region’s legacy and future as a global hub for innovation—aligns with the Department’s mission to build a resilient, regenerative Cascadia. Whether we're talking AI, biotech, transportation, or climate-smart infrastructure, it’s clear: the innovations that truly serve our region must be grounded in place-based values, ecological intelligence, and cultural reciprocity.

Throughout the two-day conference, attendees will hear from top innovators, elected officials, and global thought leaders working to elevate the region’s industries—from aerospace and tech to healthcare, climate, and beyond.

Spotlight: Cascadia on the Move – High-Speed Rail Convening

This year introduces an exciting addition: Cascadia on the Move, a convening focused on the vision and planning for a future high-speed rail line connecting Portland, Seattle, and Vancouver, BC. With $54.5 million in new federal and state funding committed in late 2024, this project is poised to transform mobility and climate infrastructure in the region.

The Department of Bioregion views this as a critical moment to embed bioregional principles into major planning decisions—ensuring that development supports not only economic growth, but also watershed health, Indigenous leadership, equitable access, and climate resilience.

A Bioregional Perspective

As this conference highlights Cascadia’s global leadership in innovation, we offer a grounding reminder:

Innovation must be in service of life—not just markets.

Bioregionalism challenges us to ask:

How do our technologies regenerate ecosystems rather than extract from them?
How can infrastructure planning support local communities, traditional stewards, and future generations?
What kinds of economic systems truly reflect our shared values of reciprocity, interdependence, and care?

The Cascadia Department of Bioregion continues to uplift this vision in policy spaces, collaborative planning efforts, and regional storytelling initiatives. As we look toward the year 2050 and beyond, we remain committed to co-creating systems that center people and planet—not just profit.

Let’s Connect

We look forward to engaging with leaders across sectors and across borders at this year’s conference. If you're attending the Cascadia Innovation Corridor 2025, come say hello, share your visions for a regenerative Cascadia, and explore how we might collaborate across boundaries, bioregions, and generations.